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Mass Flow in Analytics

Gas Chromatography

Gas Chromatography requires a stable repeatable flow of the carrier gas with negligible temperature drift. The Axetris MFC provides excellent control of the gas flow resulting in sharp peaks and high resolution of the chromatograms. Multiple calibrations allow the control of Helium, Hydrogen or Nitrogen. Due to the high turn down ratio of 1000:1 and more, a broad range of flows can be controlled.


Because of its ultra-compact size, the MFC 2022 module is the best choice if you have limited space and your instrument offers a common enclosure already. It can also be recommended for portable applications because its low power consumption and weight.


Besides carrier gas control, Axetris MFCs are also used on the inlet side of the gas chromatograph, for example for thermal desorption where the high turn-down ratio of 1000:1 is a key benefit. On the detector side of gas chromatographs, in particular TCD (Thermal conductivity detector) and MSD (Mass spectroscopy detector), Axetris customers benefit from the excellent repeatability and the leading low flow capability of the Axetris mass flow controller products.



Mass Flow in Analytics

Mass Spectrometry

A variety of MS techniques – such as Quadrupole MS, Time-of-Flight (TOF) MS, Ion Mobility Spectroscopy (IMS), etc. have been developed in the past decades, providing new tools for materials analyses. Flow control for mass spectrometry (MS) requires high repeatability and small temperature- and pressure dependency. This is important to achieve a high resolution and instrument resolution.


Depending on the size and electrical interface requirements, the Axetris MFC modules or MFC standalone types are the ideal choices for MS applications.



Mass Flow in Analytics

Atomic Spectroscopy

Besides Mass Spectrometry, a further variety of analysis techniques are categorized as atomic spectroscopy. Analysis techniques which use inductively coupled plasma (ICP), such as ICP-OES and ICP-MS, are among these.

With increasing environmental awareness backed by regulations, an increasingly important use of atomic spectroscopy techniques is in mercury analysis.


Achieving a high mass flow control performance, e.g. high repeatability or an excellent turn-down ratio, is a prerequisite to achieve a high analyzer performance. For this, a number of Axetris customers rely on our products while designing such systems.


Read our application note and learn how plasma gas control precision and unmatched dynamic range deliver key advantages:

Axetris MFD 元素分析: 元素分析
Mass Flow in Analytics

Elemental Analysis

Elemental analysis is a generic term for a group of applications which deal with the analysis of a variety of materials (chemicals, liquids, polymers, waste material, etc.) for their elemental or isotopic properties.

Typical examples of elemental analysis techniques where mass flow control plays a key role are Total Organic Carbon (TOC) or Total Organic Halides (TOX).

Mass Flow in Analytics

Thermal Analysis

A variety of thermal analysis techniques, such as Thermo Gravimetric Analysis (TGA), Differential Thermal Analysis (DTA) and Differential Scanning Calorimetry (DSC) rely on high-performance mass flow control.


Thermo Gravimetric Analysis (TGA)

Thermo Gravimetric Analysis (TGA) is a technique in which the mass of a substance is monitored as a function of temperature or time as the sample specimen is subjected to a controlled temperature program in a controlled atmosphere.


To design world-class TGA systems, OEM’s rely on high-performance mass flow solutions which can deliver benefits such as:

  • Maintenance of constant purge gas flow rates with excellent repeatability
  • Gas Switching capability (multiple gas calibrations on the same device) to provide analytical flexibility
  • High resolution to increase purge gas flow rates in small increments
  • High turn-down ratios to span a wide flow range

Axetris’ mass flow solutions provide the above advantages and more, thereby enabling the design of high-performance TGA systems.


Read our Success Story “Pushing the Limits of Thermal Analysis" to learn more about Axetris solutions in the field of thermal analysis. 


    Mass Flow in Analytics

    Bioreactor and Fermentor

    Bioreactors and fermentors are used in a variety of biotechnology and industrial applications, e.g. in cell culture or microbiology experiments. A precise control of gas flow is essential for controlling the biological process and to achieve the desired result.


    Axetris offers solutions for laboratory-scale bioreactors and fermentors, and for standard gases such as O2, CO2 and air. Besides single-channel mass flow meters and controllers, Axetris can also offer mass flow manifolds (in mixer or splitter configurations) to achieve a high-accuracy gas mix for a tight process control.

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